09:12 PLASMAGENE<08250> - Announcement The Stock Exchange of Hong Kong Limited (the "Stock Exchange") takes no responsibility for the contents of this announcement, makes no representation as to its accuracy or completeness and expressly disclaims any liability whatsoever for any loss howsoever arising from or in reliance upon the whole or any part of the contents of this announcement. PLASMAGENE BIOSCIENCES LIMITED (incorporated in the Cayman Islands with limited liability) (Stock Code: 8250) CONTINUING CONNECTED TRANSACTIONS The Directors wish to announce that the Company has renewed the sub-tenancy agreement with Wellchamp to sub-lease part of its office at 5/F, Club Lusitano, 16 Ice House Street, Central, Hong Kong to Wellchamp for a period of two years commencing on 13 February, 2005 to 12 February, 2007 for a monthly rental of HK$29,500 on 25 April 2005. The entering into of the sub-tenancy agreement is to facilitate the Group more effectively using the floor area of its office and to generate additional income and provide additional cash inflow to the Group. The continuing connected transactions are exempted under Rule 20.34 of the GEM Listing Rules from the independent shareholders' approval requirement, but is subject to the reporting and announcement requirements as set out in Rules 20.45 to 20.47 of the GEM Listing Rules. By order of the Board Plasmagence Biosciences Limited Dr. Yeung Wah Hin, Alex Chairman Hong Kong, 4 May 2005 This announcement, for which the Directors collectively and individually accept full responsibility, includes particulars given in compliance with the GEM Listing Rules for the purpose of giving information with regard to the Company. The Directors, having made all reasonable enquiries, confirm that, to the best of their knowledge and belief, (i) the information contained in this announcement is accurate and complete in all material respects and not misleading; (ii) there are no other matters the omission of which would make any statement in this announcement misleading; and (iii) all opinions expressed in this announcement have been arrived at after due and careful consideration and are founded on bases and assumptions that are fair and reasonable. The above announcement is a summary only. For the full version of this announcement, please refer to the "Latest Company Announcements" page on the GEM website of http://www.hkgem.com.